TB-500

TB-500 is a synthetic analogue of a conserved region of Thymosin Beta-4, a 43-amino-acid protein encoded by the TMSB4X gene and found at high concentrations in platelets, wound fluid, and most mammalian tissue types. The TB-500 peptide fragment incorporates the actin-binding domain of the full Thymosin Beta-4 sequence, making it a subject of interest in research examining cytoskeletal dynamics, actin sequestration, and cell migration.

In vitro studies using TB-500 have investigated its influence on endothelial and epithelial cell cultures, including assessments of proliferation, migration, and tubule formation assays. Additional pre-clinical research has examined interactions with inflammatory mediators and growth factor signalling pathways. The compound exhibits high water solubility in its reconstituted form, facilitating its use across a range of aqueous research preparations and cell culture systems.

Pepti-Genix supplies TB-500 as a lyophilised white powder of ≥99% purity, independently verified by HPLC analysis. A Certificate of Analysis confirming identity and purity is included with every order. This compound is supplied strictly for in vitro laboratory research purposes only. It is not intended for human or veterinary use, consumption, injection, or administration of any kind.